Ontology highlight
ABSTRACT:
SUBMITTER: Oki S
PROVIDER: S-EPMC5522273 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Oki Shinya S Sone Kenbun K Oda Katsutoshi K Hamamoto Ryuji R Ikemura Masako M Maeda Daichi D Takeuchi Makoto M Tanikawa Michihiro M Mori-Uchino Mayuyo M Nagasaka Kazunori K Miyasaka Aki A Kashiyama Tomoko T Ikeda Yuji Y Arimoto Takahide T Kuramoto Hiroyuki H Wada-Hiraike Osamu O Kawana Kei K Fukayama Masashi M Osuga Yutaka Y Fujii Tomoyuki T
Oncotarget 20170601 25
The histone methyltransferase EZH2, a key epigenetic modifier, is known to be associated with human tumorigenesis. However, the physiological importance of EZH2 and its clinical relevance in endometrial cancer remain unclear. Hence, in the present study, we investigated the expression and function of EZH2 in endometrial cancer. In a quantitative real-time PCR analysis of 11 endometrial cancer cell lines and 52 clinical endometrial cancer specimens, EZH2 was significantly overexpressed in cancer ...[more]