Ontology highlight
ABSTRACT:
SUBMITTER: Shi S
PROVIDER: S-EPMC5522338 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Oncotarget 20170601 25
Recent studies have shown that increased syndecan-1 (SDC1) expression in human glioma is associated with higher tumor grades and poor prognoses, but its oncogenic functions and the underlying molecular mechanisms remain unknown. Here, we examined SDC1 expression in datasets from The Cancer Genome Atlas and the National Center for Biotechnology Information Gene Expression Omnibus. Elevated SDC1 expression in glioma was closely associated with increases in tumor progression and shorter survival. W ...[more]