Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development.
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ABSTRACT:
SUBMITTER: Kim MK
PROVIDER: S-EPMC5526357 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Publications
Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development.
Kim Minyoung Kevin MK Zhao Aishan A Wang Ashley A Brown Zachary Z ZZ Muir Tom W TW Stone Howard A HA Bassler Bonnie L BL
Nature microbiology 20170522
Bacteria use a process called quorum sensing to communicate and orchestrate collective behaviours, including virulence factor secretion and biofilm formation. Quorum sensing relies on the production, release, accumulation and population-wide detection of signal molecules called autoinducers. Here, we develop concepts to coat surfaces with quorum-sensing-manipulation molecules as a method to control collective behaviours. We probe this strategy using Staphylococcus aureus. Pro- and anti-quorum-se ...[more]
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