Ontology highlight
ABSTRACT:
SUBMITTER: Jun JC
PROVIDER: S-EPMC5526543 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Jun Janice C JC Jones Mark B MB Oswald Douglas M DM Sim Edward S ES Jonnalagadda Amruth R AR Kreisman Lori S C LSC Cobb Brian A BA
PloS one 20170725 7
While Toll-like receptors (TLRs) represent one of the best characterized innate immune pathways, evidence suggests that TLRs are not restricted to innate leukocytes and some epithelial cells, but are also expressed in T cells. Specifically, published evidence focusing on FoxP3+ regulatory T cells demonstrate that they express functional TLR2, which is already known among the TLR family for its association with immune suppression; however, little is known about the relationship between T cell-int ...[more]