Ontology highlight
ABSTRACT:
SUBMITTER: Rosado-Sanchez I
PROVIDER: S-EPMC5527653 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Rosado-Sánchez I I Herrero-Fernández I I Álvarez-Ríos A I AI Genebat M M Abad-Carrillo M A MA Ruiz-Mateos E E Pulido F F González-García J J Montero M M Bernal-Morell E E Vidal F F Leal M M Pacheco Y M YM
Antimicrobial agents and chemotherapy 20170725 8
We explored if baseline CD4/CD8 T-cell ratio is associated with immunodiscordant response to antiretroviral therapy in HIV-infected subjects. Comparing immunodiscordant and immunoconcordant subjects matched by pretreatment CD4 counts, we observed a lower pretreatment CD4/CD8 T-cell ratio in immunodiscordant subjects. Furthermore, pretreatment CD4/CD8 T-cell ratio, but not CD4 counts, correlated with the main immunological alterations observed in immunodiscordants, including increased regulatory ...[more]