Ontology highlight
ABSTRACT:
SUBMITTER: Andrews SHJ
PROVIDER: S-EPMC5529506 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Andrews Stephen H J SHJ Kunze Melanie M Mulet-Sierra Aillette A Williams Lynn L Ansari Khalid K Osswald Martin M Adesida Adetola B AB
Scientific reports 20170726 1
Skin cancer and its associated treitments can have devastating consequences for survivors; this is particularly true when cancer occurs on the nose. Recent work has applied cell-based tissue engineering (TE) strategies to develop nasal cartilage constructs for reconstruction of the nose. In this study, we have generated human nasal cartilage on a clinically approved collagen scaffold to investigate the donor-to-donor variability of TE cartilage and evaluated strategies to mitigate it. We also ev ...[more]