TGF?-induced osteogenic potential of human amniotic fluid stem cells via CD73-generated adenosine production.
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ABSTRACT:
SUBMITTER: Hau KL
PROVIDER: S-EPMC5529586 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
TGFβ-induced osteogenic potential of human amniotic fluid stem cells via CD73-generated adenosine production.
Hau Kwan-Leong KL Ranzoni Anna Maria AM Vlahova Filipa F Hawkins Kate K De Coppi Paolo P David Anna L AL Guillot Pascale V PV Guillot Pascale V PV
Scientific reports 20170726 1
The human amniotic fluid stem cell (hAFSC) population consists of two morphologically distinct subtypes, spindle-shaped and round-shaped cells (SS-hAFSCs and RS-hAFSCs). Whilst SS-hAFSCs are routinely expanded in mesenchymal-type (MT) conditions, we previously showed that they acquire broader differentiation potential when cultured under embryonic-type (ET) conditions. However, the effects of culture conditions on RS-hAFSCs have not been determined. Here, we show that culturing RS-hAFSCs under E ...[more]
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