Ontology highlight
ABSTRACT:
SUBMITTER: Pisanello F
PROVIDER: S-EPMC5533215 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Pisanello Ferruccio F Mandelbaum Gil G Pisanello Marco M Oldenburg Ian A IA Sileo Leonardo L Markowitz Jeffrey E JE Peterson Ralph E RE Della Patria Andrea A Haynes Trevor M TM Emara Mohamed S MS Spagnolo Barbara B Datta Sandeep Robert SR De Vittorio Massimo M Sabatini Bernardo L BL
Nature neuroscience 20170619 8
Optogenetics promises precise spatiotemporal control of neural processes using light. However, the spatial extent of illumination within the brain is difficult to control and cannot be adjusted using standard fiber optics. We demonstrate that optical fibers with tapered tips can be used to illuminate either spatially restricted or large brain volumes. Remotely adjusting the light input angle to the fiber varies the light-emitting portion of the taper over several millimeters without movement of ...[more]