Ontology highlight
ABSTRACT:
SUBMITTER: Mousavi S
PROVIDER: S-EPMC5534524 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Mousavi Saeedeh S Kohan Leila L Yavarian Majid M Habib Asadollah A
Molecular biology research communications 20170601 2
Type 2 diabetes mellitus is a worldwide epidemic disorder with considerable health and economic consequences. Metformin is one of the most commonly prescribed oral antidiabetic drugs. Pharmacogenetic studies showed that variants in genes related to the pharmacokinetics of metformin were associated with glucose-lowering effect of metformin. The aim of this study was to evaluate pharmacogenetic variation in <i>SLC47A1</i> (rs2289669) and metformin response in type 2 diabetes patients. Seventy one ...[more]