Ontology highlight
ABSTRACT:
SUBMITTER: Peng Y
PROVIDER: S-EPMC5535721 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Journal of Cancer 20170603 9
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus-associated malignancy occurring at high incidence in Southeast Asia and southern China. In spite of the good response to radio- and chemo-therapy at the early stage, resistance and recurrence develop in NPC patients in the advanced setting. Cancer stem cells (CSCs) play an important role in drug resistance and cancer recurrence. Here we report that lovastatin, a natural compound and a lipophilic statin that has already been used in the clin ...[more]