Ontology highlight
ABSTRACT:
SUBMITTER: Adamska A
PROVIDER: S-EPMC5535831 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Adamska Aleksandra A Domenichini Alice A Falasca Marco M
International journal of molecular sciences 20170622 7
Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is the fourth leading cause of cancer-related deaths in the world. Due to the broad heterogeneity of genetic mutations and dense stromal environment, PDAC belongs to one of the most chemoresistant cancers. Most of the available treatments are palliative, with the objective of relieving disease-related symptoms and prolonging survival. Currently, available therapeutic options are surgery, radiation, chemotherapy ...[more]