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Unexpected papilledema in a young male with Type 1 diabetes.


ABSTRACT: In young patients with T1D, neurological manifestations of cerebral hypertension should suggest the possibility of a cerebral venous sinus thrombosis (CVST). In these patients an inherited prothrombotic risk factor, including factor V Leiden G1691A gene mutation, should be considered during an event of thrombosis. Improving the glycemic control is the first factor that should be controlled in a patient who carries a genetic prothrombotic risk factor. Anticoagulant treatment should be started as son as CVST has been diagnosed. Long-term antithrombotic treatment with tinzaparin 175 IU/kg/day, a low-molecular weight heparin (LMWH), could be reliable and well tolerated, although an indefinite special follow-up, including neurological controls, is advisable even in asymptomatic patients.

SUBMITTER: Paniagua JA 

PROVIDER: S-EPMC5538076 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature

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Unexpected papilledema in a young male with Type 1 diabetes.

Paniagua Juan A JA   Bahamondes Rodrigo R   Cano-Sánchez Antonio A   Velasco Francisco F  

Clinical case reports 20170704 8


In young patients with T1D, neurological manifestations of cerebral hypertension should suggest the possibility of a cerebral venous sinus thrombosis (CVST). In these patients an inherited prothrombotic risk factor, including factor V Leiden G1691A gene mutation, should be considered during an event of thrombosis. Improving the glycemic control is the first factor that should be controlled in a patient who carries a genetic prothrombotic risk factor. Anticoagulant treatment should be started as  ...[more]

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