Ontology highlight
ABSTRACT:
SUBMITTER: Saito M
PROVIDER: S-EPMC5538770 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Saito Masaki M Otsu Wataru W Hsu Kuo-Shun KS Chuang Jen-Zen JZ Yanagisawa Teruyuki T Shieh Vincent V Kaitsuka Taku T Wei Fan-Yan FY Tomizawa Kazuhito K Sung Ching-Hwa CH
EMBO reports 20170612 8
The primary cilium is a plasma membrane-protruding sensory organelle that undergoes regulated assembly and resorption. While the assembly process has been studied extensively, the cellular machinery that governs ciliary resorption is less well understood. Previous studies showed that the ciliary pocket membrane is an actin-rich, endocytosis-active periciliary subdomain. Furthermore, Tctex-1, originally identified as a cytoplasmic dynein light chain, has a dynein-independent role in ciliary resor ...[more]