Activation of Inflammatory and Pro-Thrombotic Pathways in Acute Stress Cardiomyopathy.
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ABSTRACT:
SUBMITTER: Fitzgibbons TP
PROVIDER: S-EPMC5541033 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Activation of Inflammatory and Pro-Thrombotic Pathways in Acute Stress Cardiomyopathy.
Fitzgibbons Timothy P TP Edwards Yvonne J K YJK Shaw Peter P Iskandar Aline A Ahmed Mohamed M Bote Josiah J Shah Tejen T Sinha Sumita S Gerszten Robert E RE Keaney John F JF Zile Michael R MR Aurigemma Gerard P GP
Frontiers in cardiovascular medicine 20170803
Stress cardiomyopathy (SCM) is a unique cardiac disorder that more often occurs in women. SCM presents in a similar fashion as acute myocardial infarction (AMI), with chest pain, ECG changes, and congestive heart failure. The primary distinguishing feature is the absence of thrombotic coronary occlusion in SCM. How this reduction in cardiac function occurs in the absence of coronary occlusion remains unknown. Therefore, we tested the hypothesis that a targeted proteomic comparison of patients wi ...[more]
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