Ontology highlight
ABSTRACT:
SUBMITTER: Dengler M
PROVIDER: S-EPMC5542263 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Dengler Mirko M Staufer Katharina K Huber Heidemarie H Stauber Rudolf R Bantel Heike H Weiss Karl Heinz KH Starlinger Patrick P Pock Hannelore H Klöters-Plachky Petra P Gotthardt Daniel N DN Rauch Peter P Lackner Carolin C Stift Judith J Brostjan Christine C Gruenberger Thomas T Kumada Takashi T Toyoda Hidenori H Tada Toshifumi T Weiss Thomas S TS Trauner Michael M Mikulits Wolfgang W
Oncotarget 20170701 28
Patients with chronic liver disease (CLD) and cirrhosis are at high risk for hepatocellular carcinoma (HCC). Current diagnostic tools for HCC detection include imaging techniques and serum biomarkers such as α-fetoprotein (AFP). Yet, these methods are limited in sensitivity and specificity to accurately detect early HCC. Here we focused on the potential of soluble Axl (sAxl) as a biomarker in CLD patients by analyzing serum samples of 1067 patients and healthy controls from centers in Europe and ...[more]