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ABSTRACT: Purpose
The purpose of this study is to assess the risk factors and characteristics of adherent perinephric fat (APF) in healthy individuals.Patients and methods
Men who underwent laparoscopic donor nephrectomy were included. Video review was used to divide patients on the basis of APF severity. Relationship between APF scores and clinical and radiographic features was evaluated.Results
Of the 92 patients, 43 (46.7%) and 8 (8.7%) were categorized as APF and severe APF, respectively. The median total operative time was significantly associated with APF severity. Sex, body mass index, and perinephric fat area, stranding, and thickness were significantly associated with severe APF. In the multivariate analysis, perinephric fat areas and stranding were independent risk factors for severe APF (HR, 1.189 and 14.450, respectively). In the 44 analyzed cytokines, levels of sIL-6R in the perinephric adipose tissue-conditioned medium were significantly higher for APF group than that for non-APF group (P=0.049).Conclusions
Host-related risk factors for APF could predict surgical difficulty in patients undergoing partial nephrectomy.
SUBMITTER: Narita S
PROVIDER: S-EPMC5542780 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Narita Shintaro S Kumazawa Teruaki T Tsuchiya Norihiko N Mingguo Huang H Saito Mitsuru M Inoue Takamitsu T Tsuruta Hiroshi H Numakura Kazuyuki K Maeno Atsushi A Nanjo Hiroshi H Satoh Shigeru S Habuchi Tomonori T
Surgical laparoscopy, endoscopy & percutaneous techniques 20170801 4
<h4>Purpose</h4>The purpose of this study is to assess the risk factors and characteristics of adherent perinephric fat (APF) in healthy individuals.<h4>Patients and methods</h4>Men who underwent laparoscopic donor nephrectomy were included. Video review was used to divide patients on the basis of APF severity. Relationship between APF scores and clinical and radiographic features was evaluated.<h4>Results</h4>Of the 92 patients, 43 (46.7%) and 8 (8.7%) were categorized as APF and severe APF, re ...[more]