Ontology highlight
ABSTRACT:
SUBMITTER: Hasse JM
PROVIDER: S-EPMC5544308 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Hasse J Michael JM Briggs Farran F
Proceedings of the National Academy of Sciences of the United States of America 20170711 30
The corticogeniculate (CG) pathway connects the visual cortex with the visual thalamus (LGN) in the feedback direction and enables the cortex to directly influence its own input. Despite numerous investigations, the role of this feedback circuit in visual perception remained elusive. To probe the function of CG feedback in a causal manner, we selectively and reversibly manipulated the activity of CG neurons in anesthetized ferrets in vivo using a combined viral-infection and optogenetics approac ...[more]