Ontology highlight
ABSTRACT:
SUBMITTER: Armaiz-Flores SA
PROVIDER: S-EPMC5545782 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Armaiz-Flores Sara A SA Kelly Nichole R NR Galescu Ovidiu A OA Demidowich Andrew P AP Altschul Anne M AM Brady Sheila M SM Hubbard Van S VS Pickworth Courtney K CK Tanofsky-Kraff Marian M Shomaker Lauren B LB Reynolds James C JC Yanovski Jack A JA
Hormone research in paediatrics 20170330 4
<h4>Background/aims</h4>Animal studies suggest that leptin may adversely affect bone mineral density (BMD). Clinical studies have yielded conflicting results. We therefore investigated associations between leptin and bone parameters in children.<h4>Methods</h4>830 healthy children (age = 11.4 ± 3.1 years; 75% female; BMI standard deviation score [BMIz] = 1.5 ± 1.1) had fasting serum leptin measured with ELISA and body composition by dual-energy X-ray absorptiometry. The main effects for leptin a ...[more]