Ontology highlight
ABSTRACT:
SUBMITTER: Li H
PROVIDER: S-EPMC5546157 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Li Heming H Meng Qing H QH Noh Hyangsoon H Batth Izhar Singh IS Somaiah Neeta N Torres Keila E KE Xia Xueqing X Wang Ruoyu R Li Shulin S
Cancer letters 20170623
Circulating tumor cells (CTCs) enter the vasculature or lymphatic system after shedding from the primary tumor. CTCs may serve as "seed" cells for tumor metastasis. The utility of CTCs in clinical applications for sarcoma is not fully investigated, partly owing to the necessity for fresh blood samples and the lack of a CTC-specific antibody. To overcome these drawbacks, we developed a technique for sarcoma CTCs capture and detection using cryopreserved peripheral blood mononuclear cells (PBMCs) ...[more]