Emerging Targets of Diuretic Therapy.
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ABSTRACT:
SUBMITTER: Cheng CJ
PROVIDER: S-EPMC5546989 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Publications
Emerging Targets of Diuretic Therapy.
Cheng C-J CJ Rodan A R AR Huang C-L CL
Clinical pharmacology and therapeutics 20170710 3
Diuretics are commonly prescribed for treatment in patients with hypertension, edema, or heart failure. Studies on hypertensive and salt-losing disorders and on urea transporters have contributed to better understanding of mechanisms of renal salt and water reabsorption and their regulation. Proteins involved in the regulatory pathways are emerging targets for diuretic and aquaretic therapy. Integrative high-throughput screening, protein structure analysis, and chemical modification have identif ...[more]
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