Ontology highlight
ABSTRACT:
SUBMITTER: Yang L
PROVIDER: S-EPMC5549387 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Biomarker research 20170808
The fact that various immune cells, including macrophages, can be found in tumor tissues has long been known. With the introduction of concept that macrophages differentiate into a classically or alternatively activated phenotype, the role of tumor-associated macrophages (TAMs) is now beginning to be elucidated. TAMs act as "protumoral macrophages", contributing to disease progression. As the relationship between TAMs and malignant tumors becomes clearer, TAMs are beginning to be seen as potenti ...[more]