Platelets as autonomous drones for hemostatic and immune surveillance.
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ABSTRACT:
SUBMITTER: Li JL
PROVIDER: S-EPMC5551582 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Publications
Platelets as autonomous drones for hemostatic and immune surveillance.
Li Jackson LiangYao JL Zarbock Alexander A Hidalgo Andrés A
The Journal of experimental medicine 20170801 8
Platelets participate in many important physiological processes, including hemostasis and immunity. However, despite their broad participation in these evolutionarily critical roles, the anucleate platelet is uniquely mammalian. In contrast with the large nucleated equivalents in lower vertebrates, we find that the design template for the evolutionary specialization of platelets shares remarkable similarities with human-engineered unmanned aerial vehicles in terms of overall autonomy, maneuverab ...[more]
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