Ontology highlight
ABSTRACT:
SUBMITTER: Maouia A
PROVIDER: S-EPMC7501063 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Maouia Amal A Rebetz Johan J Kapur Rick R Semple John W JW
Transfusion medicine reviews 20200919 4
Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints them with a variety of inflammatory processes. For example, platelets can act as circulating sentinels by expressing Toll-like receptors (TLR) that bind pathogens and this allows platelets to effectively kill them or present them to cells of the immune system. Furthermore, activated platelets secrete and express many pro- and anti-inflammatory molecules that attract and capture circulating leukocytes an ...[more]