Ontology highlight
ABSTRACT:
SUBMITTER: Bussolati G
PROVIDER: S-EPMC5552132 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Bussolati Gianni G Annaratone Laura L Berrino Enrico E Miglio Umberto U Panero Mara M Cupo Marco M Gugliotta Patrizia P Venesio Tiziana T Sapino Anna A Marchiò Caterina C
PloS one 20170810 8
Tissue fixation in phosphate buffered formalin (PBF) remains the standard procedure in histopathology, since it results in an optimal structural, antigenic and molecular preservation that justifies the pivotal role presently played by diagnoses on PBF-fixed tissues in precision medicine. However, toxicity of formaldehyde causes an environmental concern and may demand substitution of this reagent. Having observed that the reported drawbacks of commercially available glyoxal substitutes of PBF (Pr ...[more]