Ontology highlight
ABSTRACT:
SUBMITTER: Starkov P
PROVIDER: S-EPMC5555155 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20170707 28
We report a divergent and modular protocol for the preparation of acyclic molecular frameworks containing newly created quaternary carbon stereocenters. Central to this approach is a sequence composed of a (1) regioselective and -retentive preparation of allyloxycarbonyl-trapped fully substituted stereodefined amide enolates and of a (2) enantioselective palladium-catalyzed decarboxylative allylic alkylation reaction using a novel bisphosphine ligand. ...[more]