Dataset Information

TaiNi: Maximizing research output whilst improving animals' welfare in neurophysiology experiments.

ABSTRACT: Understanding brain function at the cell and circuit level requires representation of neuronal activity through multiple recording sites and at high sampling rates. Traditional tethered recording systems restrict movement and limit the environments suitable for testing, while existing wireless technology is still too heavy for extended recording in mice. Here we tested TaiNi, a novel ultra-lightweight (<2?g) low power wireless system allowing 72-hours of recording from 16 channels sampled at ~19.5 KHz (9.7 KHz bandwidth). We captured local field potentials and action-potentials while mice engaged in unrestricted behaviour in a variety of environments and while performing tasks. Data was synchronized to behaviour with sub-second precision. Comparisons with a state-of-the-art wireless system demonstrated a significant improvement in behaviour owing to reduced weight. Parallel recordings with a tethered system revealed similar spike detection and clustering. TaiNi represents a significant advance in both animal welfare in electrophysiological experiments, and the scope for continuously recording large amounts of data from small animals.

SUBMITTER: Jiang Z

PROVIDER: S-EPMC5556067 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature

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TaiNi: Maximizing research output whilst improving animals' welfare in neurophysiology experiments.

Jiang Zhou Z Huxter John R JR Bowyer Stuart A SA Blockeel Anthony J AJ Butler James J Imtiaz Syed A SA Wafford Keith A KA Phillips Keith G KG Tricklebank Mark D MD Marston Hugh M HM Rodriguez-Villegas Esther E

Scientific reports 20170814 1

Understanding brain function at the cell and circuit level requires representation of neuronal activity through multiple recording sites and at high sampling rates. Traditional tethered recording systems restrict movement and limit the environments suitable for testing, while existing wireless technology is still too heavy for extended recording in mice. Here we tested TaiNi, a novel ultra-lightweight (<2 g) low power wireless system allowing 72-hours of recording from 16 channels sampled at ~19 ...[more]

PMID: 28808347

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Dataset Information

TaiNi: Maximizing research output whilst improving animals' welfare in neurophysiology experiments.

Publications

TaiNi: Maximizing research output whilst improving animals' welfare in neurophysiology experiments.

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