Ontology highlight
ABSTRACT:
SUBMITTER: Devine PWA
PROVIDER: S-EPMC5556138 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Devine Paul W A PWA Fisher Henry C HC Calabrese Antonio N AN Whelan Fiona F Higazi Daniel R DR Potts Jennifer R JR Lowe David C DC Radford Sheena E SE Ashcroft Alison E AE
Journal of the American Society for Mass Spectrometry 20170508 9
Collision cross-section (CCS) measurements obtained from ion mobility spectrometry-mass spectrometry (IMS-MS) analyses often provide useful information concerning a protein's size and shape and can be complemented by modeling procedures. However, there have been some concerns about the extent to which certain proteins maintain a native-like conformation during the gas-phase analysis, especially proteins with dynamic or extended regions. Here we have measured the CCSs of a range of biomolecules i ...[more]