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Inflammation and pro-resolution inflammation after hepatobiliary surgery.

ABSTRACT: The magnitude of the perioperative inflammatory response plays a role in surgical outcomes. However, few studies have explored the mechanisms of the resolution of inflammation in the context of surgery. Here, we described the temporal kinetics of interleukin-6, cortisol, lipoxin A4, and resolvin D in patients who underwent oncologic liver resections.All patients gave written informed consent. Demographic and perioperative surgical data were collected, along with blood samples, before surgery and on the mornings of postoperative days 1, 3, and 5. Interleukin-6, cortisol, lipoxin-A4, and resolvin D were measured in plasma. A P value

SUBMITTER: Cata JP

PROVIDER: S-EPMC5556621 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature

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Inflammation and pro-resolution inflammation after hepatobiliary surgery.

Cata Juan P JP Velasquez Jose F JF Ramirez Maria F MF Vauthey Jean-Nicolas JN Gottumukkala Vijaya V Conrad Claudius C Kim Bradford J BJ Aloia Thomas T

World journal of surgical oncology 20170810 1

<h4>Background</h4>The magnitude of the perioperative inflammatory response plays a role in surgical outcomes. However, few studies have explored the mechanisms of the resolution of inflammation in the context of surgery. Here, we described the temporal kinetics of interleukin-6, cortisol, lipoxin A4, and resolvin D in patients who underwent oncologic liver resections.<h4>Methods</h4>All patients gave written informed consent. Demographic and perioperative surgical data were collected, along wit ...[more]

PMID: 28807031

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2024-10-09 | GSE270972 | GEO

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