Ontology highlight
ABSTRACT:
SUBMITTER: Qi XM
PROVIDER: S-EPMC5559841 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Translational neurodegeneration 20170817
Cerebral amyloid angiopathy (CAA) is characterized by the deposition of amyloid β-protein (Aβ) in the leptomeningeal and cortical blood vessels, which is an age-dependent risk factor for intracerebral hemorrhage (ICH), ischemic stroke and contributes to cerebrovascular dysfunction leading to cognitive impairment. However clinical prevention and treatment of the disease is very difficult because of its occult onset and severity of the symptoms. In recent years, many anti-amyloid β immunotherapies ...[more]