Ontology highlight
ABSTRACT:
SUBMITTER: Mercadante CJ
PROVIDER: S-EPMC5560020 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20160317 3
Manganese is an essential dietary nutrient and trace element with important roles in mammalian development, metabolism, and antioxidant defense. In healthy individuals, gastrointestinal absorption and hepatobiliary excretion are tightly regulated to maintain systemic manganese concentrations at physiologic levels. Interactions of manganese with other essential metals following high dose ingestion are incompletely understood. We previously reported that gavage manganese exposure in rats resulted ...[more]