Ontology highlight
ABSTRACT:
SUBMITTER: Foster ML
PROVIDER: S-EPMC5683753 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Data in brief 20171024
High dose manganese (Mn) exposure can result in changes in tissue concentrations of other essential metals due to Mn-induced alterations in metal absorption and competition for metal transporters and regulatory proteins. We evaluated responses in mice with a Parkin gene defect (parkin mice) and a wildtype strain (C57BL/6J) following neonatal Mn exposure. Neonatal parkin and C57BL/6J littermates were randomly assigned to 0, 11, or 25 mg Mn/kg-day dose groups with oral exposures occurring from pos ...[more]