Ontology highlight
ABSTRACT:
SUBMITTER: Barrio L
PROVIDER: S-EPMC5560857 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
eLife 20170704
The gradient of Decapentaplegic (Dpp) in the <i>Drosophila</i> wing has served as a paradigm to characterize the role of morphogens in regulating patterning. However, the role of this gradient in regulating tissue size is a topic of intense debate as proliferative growth is homogenous. Here, we combined the Gal4/UAS system and a temperature-sensitive Gal80 molecule to induce RNAi-mediated depletion of <i>dpp</i> and characterise the spatial and temporal requirement of Dpp in promoting growth. We ...[more]