Ontology highlight
ABSTRACT:
SUBMITTER: Yang Y
PROVIDER: S-EPMC5561006 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Yang Youfeng Y Vocke Cathy D CD Ricketts Christopher J CJ Wei Darmood D Padilla-Nash Hesed M HM Lang Martin M Sourbier Carole C Killian J Keith JK Boyle Shawna L SL Worrell Robert R Meltzer Paul S PS Ried Thomas T Merino Maria J MJ Metwalli Adam R AR Linehan W Marston WM
Genes, chromosomes & cancer 20170724 10
Chromophobe renal cell carcinoma (ChRCC) represents 5% of all RCC cases and frequently demonstrates multiple chromosomal losses and an indolent pattern of local growth, but can demonstrate aggressive features and resistance to treatment in a metastatic setting. Cell line models are an important tool for the investigation of tumor biology and therapeutic drug efficacy. Currently, there are few ChRCC-derived cell lines and none is well characterized. This study characterizes a novel ChRCC-derived ...[more]