Ontology highlight
ABSTRACT:
SUBMITTER: Xie Q
PROVIDER: S-EPMC5562094 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Xie Qun Q Liu Dandan D Yu Mosheng M Wu Xiaowei X Zhao Yueqiang Y Hu Qiang Q Wang Qi Q
Molecular medicine reports 20170621 2
The functions and underlying mechanisms of homeobox B9 (HOXB9) in scar formation remain unclear; therefore, the present study aimed to investigate whether HOXB9 is highly expressed in hypertrophic scar formation. Immunohistochemistry was performed to examine the expression levels of laminin, fibronectin (FN), collagen type I (Col1) and HOXB9 in hypertrophic scar and healthy skin tissues, and in lentivirus‑constructed HOXB9‑overexpressed or ‑silenced fibroblasts (FBs). Reverse transcription‑quant ...[more]