Ontology highlight
ABSTRACT:
SUBMITTER: Yin J
PROVIDER: S-EPMC5008335 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Yin Jie J Wang Lan L Zhu Ji-Min JM Yu Qian Q Xue Ru-Yi RY Fang Ying Y Zhang Yi-An YA Chen Yan-Jie YJ Liu Tao-Tao TT Dong Ling L Shen Xi-Zhong XZ
Oncotarget 20160401 16
Pre-mRNA processing factor 19 (Prp19) is involved in many cellular events including pre-mRNA processing and DNA damage response. However, the pathological role of Prp19 in hepatocellular carcinoma (HCC) is still elusive. Here, we reported that Prp19 was increased in most HCC tissues and HCC cell lines, and its overexpression in HCC tissues was positively correlated with vascular invasion, tumor capsule breakthrough and poor prognosis. Prp19 potentiated migratory and invasive abilities of HCC cel ...[more]