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Fast assembling of neuron fragments in serial 3D sections.


ABSTRACT: Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons.

SUBMITTER: Chen H 

PROVIDER: S-EPMC5563299 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature

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Fast assembling of neuron fragments in serial 3D sections.

Chen Hanbo H   Iascone Daniel Maxim DM   da Costa Nuno Maçarico NM   Lein Ed S ES   Liu Tianming T   Peng Hanchuan H  

Brain informatics 20170401 3


Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons. ...[more]

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