Ontology highlight
ABSTRACT:
SUBMITTER: Zhai B
PROVIDER: S-EPMC5565510 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Zhai Binyuan B DuPrez Kevin K Doukov Tzanko I TI Li Huan H Huang Mengting M Shang Guijun G Ni Jinfeng J Gu Lichuan L Shen Yulong Y Fan Li L
Journal of molecular biology 20170224 7
Holliday junction (HJ) is a hallmark intermediate in DNA recombination and must be processed by dissolution (for double HJ) or resolution to ensure genome stability. Although HJ resolvases have been identified in all domains of life, there is a long-standing effort to search in prokaryotes and eukarya for proteins promoting HJ migration. Here, we report the structural and functional characterization of a novel ATPase, Sulfolobus islandicusPilT N-terminal-domain-containing ATPase (SisPINA), encod ...[more]