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Development of Au nanowire injector system to deliver plasmid into mouse embryo.


ABSTRACT: In this data article, we developed a Au nanowire injector (Au NWI) for directly delivering plasmid into the 1-cell stage of the mouse embryos designed to successfully attach and detach the plasmid on the Au NWI, highly minimizing physical and chemical damage on the embryos. This data presents that a Au NWI system does not induce detrimental damages on development of embryos and efficiently express the green fluorescence protein in vitro. The data provided herein is in association with the research article related to reduce the occurrence of mosaicism by a Au NWI," Suppressing Mosaicism by Au Nanowire Injector-driven Direct Delivery of Plasmids into Mouse Embryos" (Park et al., 2017 [1]).

SUBMITTER: Park K 

PROVIDER: S-EPMC5567388 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature

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Development of Au nanowire injector system to deliver plasmid into mouse embryo.

Park Kkotchorong K   Kim Keun Cheon KC   Lee Hyoban H   Sung Yoori Y   Kang Mijeong M   Lee Yun Mi YM   Ahn Ji Yeon JY   Lim Jeong Mook JM   Kang Taejoon T   Kim Bongsoo B   Lee Eun Ju EJ  

Data in brief 20170715


In this data article, we developed a Au nanowire injector (Au NWI) for directly delivering plasmid into the 1-cell stage of the mouse embryos designed to successfully attach and detach the plasmid on the Au NWI, highly minimizing physical and chemical damage on the embryos. This data presents that a Au NWI system does not induce detrimental damages on development of embryos and efficiently express the green fluorescence protein in vitro. The data provided herein is in association with the resear  ...[more]

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