Ontology highlight
ABSTRACT:
SUBMITTER: Rubinstein BY
PROVIDER: S-EPMC5567592 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Rubinstein Boris Y BY Mogilner Alex A
Biophysical journal 20170801 4
Myosin-powered force generation and contraction in nonmuscle cells underlies many cell biological processes and is based on contractility of random actin arrays. This contractility must rely on a microscopic asymmetry, the precise mechanism of which is not completely clear. A number of models of mechanical and structural asymmetries in actomyosin contraction have been posited. Here, we examine a contraction mechanism based on a finite size of myosin clusters and anisotropy of force generation by ...[more]