Ontology highlight
ABSTRACT:
SUBMITTER: Lin YH
PROVIDER: S-EPMC5568104 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Lin Yi-Hua YH Liao Xi-Ning XN Fan Li-Li LL Qu Yue-Jin YJ Cheng De-Yun DY Shi Yong-Hong YH
PloS one 20170823 8
<h4>Background</h4>The systemic inflammation is associated with clinical outcome and mortality in chronic obstructive pulmonary disease (COPD) patients. To investigate the effects of tiotropium (Tio) and/or budesonide/formoterol (Bud/Form) on systemic inflammation biomarkers in stable COPD patients of group D, a randomized, open-label clinical trial was conducted.<h4>Methods</h4>Eligible participants (n = 324) were randomized and received either Tio 18ug once daily (group I), Bud/Form 160/4.5ug ...[more]