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Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria.


ABSTRACT: Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (P < .001). Uncomplicated malaria (P = .04), not SM (P = .06), children had increased oxygen consumption compared with controls.

SUBMITTER: Yeo TW 

PROVIDER: S-EPMC5569702 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Decreased Microvascular Function in Tanzanian Children With Severe and Uncomplicated Falciparum Malaria.

Yeo Tsin W TW   Florence Salvatore M SM   Kalingonji Ayam R AR   Chen Youwei Y   Granger Donald L DL   Anstey Nicholas M NM   Mwaikambo Esther D ED   Weinberg J Brice JB  

Open forum infectious diseases 20170422 2


Microvascular function and oxygen consumption affect oxygen homeostasis but have not been assessed in African children with malaria. Microvascular function in Tanzanian children with severe malaria (SM) or uncomplicated malaria were 39% and 72%, respectively, of controls (<i>P</i> < .001). Uncomplicated malaria (<i>P</i> = .04), not SM (<i>P</i> = .06), children had increased oxygen consumption compared with controls. ...[more]

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