Pseudomonas aeruginosa Clinical Isolates in Nepal Coproducing Metallo-?-Lactamases and 16S rRNA Methyltransferases.

ABSTRACT: A total of 11 multidrug-resistant Pseudomonas aeruginosa clinical isolates were obtained in Nepal. Four of these isolates harbored genes encoding one or more carbapenemases (DIM-1, NDM-1, and/or VIM-2), and five harbored genes encoding a 16S rRNA methyltransferase (RmtB4 or RmtF2). A novel RmtF variant, RmtF2, had a substitution (K65E) compared with the same gene in RmtF. To our knowledge, this is the first report describing carbapenemase- and 16S rRNA methyltransferase-coproducing P. aeruginosa clinical isolates in Nepal.

SUBMITTER: Tada T 

PROVIDER: S-EPMC5571325 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature