Ontology highlight
ABSTRACT:
SUBMITTER: Zhao X
PROVIDER: S-EPMC5572209 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zhao Xibao X Pu Debing D Zhao Zizhao Z Zhu Huihui H Li Hongrui H Shen Yaping Y Zhang Xingjie X Zhang Ruihan R Shen Jianzhong J Xiao Weilie W Chen Weilin W
Frontiers in pharmacology 20170823
Inflammation causes many diseases that are serious threats to human health. However, the molecular mechanisms underlying regulation of inflammation and inflammasome activation are not fully understood which has delayed the discovery of new anti-inflammatory drugs of urgent clinic need. Here, we found that the natural compound Teuvincenone F, which was isolated and purified from the stems and leaves of <i>Premna szemaoensis</i>, could significantly inhibit lipopolysaccharide (LPS)-induced pro-inf ...[more]