Dataset Information

Tuberculosis/cryptococcosis co-infection in China between 1965 and 2016.

ABSTRACT: Cases of tuberculosis/cryptococcosis co-infection are rapidly increasing in China. However, most studies addressing this co-infection have been published in Chinese journals, and this publication strategy has obscured this disease trend for scientists in other parts of the world. Our investigation found that 62.9% of all co-infection cases worldwide were reported in the Chinese population (n=197) between 1965 and 2016, and 56.3% of these Chinese cases were reported after 2010. Nearly all cases originated from the warm and wet monsoon regions of China. HIV-positive subjects tended to correlate with more severe manifestations of a tuberculosis/cryptococcosis co-infection than those without HIV. Notablely, dual tubercular/cryptococcal meningitis was the most frequent (54.0%) and most easily misdiagnosed (95.2%, n=40/42) co-infection. We also found that the combined use of cerebrospinal fluid pressure and concentrations of glucose, protein and chlorine might be an inexpensive and effective indicator to differentiate tubercular/cryptococcal co-infection meningitis from tubercular meningitis and cryptococcal meningitis.

SUBMITTER: Fang W

PROVIDER: S-EPMC5583669 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature

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Tuberculosis/cryptococcosis co-infection in China between 1965 and 2016.

Fang Wenjie W Zhang Lei L Liu Jia J Denning David W DW Hagen Ferry F Jiang Weiwei W Hong Nan N Deng Shuwen S Lei Xia X Deng Danqi D Liao Wanqing W Xu Jianping J Boekhout Teun T Chen Min M Pan Weihua W

Emerging microbes & infections 20170823 8

Cases of tuberculosis/cryptococcosis co-infection are rapidly increasing in China. However, most studies addressing this co-infection have been published in Chinese journals, and this publication strategy has obscured this disease trend for scientists in other parts of the world. Our investigation found that 62.9% of all co-infection cases worldwide were reported in the Chinese population (n=197) between 1965 and 2016, and 56.3% of these Chinese cases were reported after 2010. Nearly all cases o ...[more]

PMID: 28831193

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Dataset Information

Tuberculosis/cryptococcosis co-infection in China between 1965 and 2016.

Publications

Tuberculosis/cryptococcosis co-infection in China between 1965 and 2016.

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