Ontology highlight
ABSTRACT:
SUBMITTER: Wang M
PROVIDER: S-EPMC5587717 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Wang Ming M Sun Zhaolin Z Yu Tian T Ding Fangrong F Li Ling L Wang Xi X Fu Mingbo M Wang Haiping H Huang Jinming J Li Ning N Dai Yunping Y
Scientific reports 20170906 1
Human lactoferrin (hLF) is a valuable protein for pharmaceutical products and functional foods, and worldwide demand for this protein has steadily increased. However, large-scale recombinant human lactoferrin (rhLF) production using current animal bioreactor techniques is limited by the low expression of foreign proteins, the use of antibiotic resistance genes and the down-regulation of endogenous milk proteins. Here, we generated a herd of marker-free, hLF bacterial artificial chromosome (BAC) ...[more]