Ontology highlight
ABSTRACT:
SUBMITTER: Roedig P
PROVIDER: S-EPMC5588887 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Roedig Philip P Ginn Helen M HM Pakendorf Tim T Sutton Geoff G Harlos Karl K Walter Thomas S TS Meyer Jan J Fischer Pontus P Duman Ramona R Vartiainen Ismo I Reime Bernd B Warmer Martin M Brewster Aaron S AS Young Iris D ID Michels-Clark Tara T Sauter Nicholas K NK Kotecha Abhay A Kelly James J Rowlands David J DJ Sikorsky Marcin M Nelson Silke S Damiani Daniel S DS Alonso-Mori Roberto R Ren Jingshan J Fry Elizabeth E EE David Christian C Stuart David I DI Wagner Armin A Meents Alke A
Nature methods 20170619 8
We report a method for serial X-ray crystallography at X-ray free-electron lasers (XFELs), which allows for full use of the current 120-Hz repetition rate of the Linear Coherent Light Source (LCLS). Using a micropatterned silicon chip in combination with the high-speed Roadrunner goniometer for sample delivery, we were able to determine the crystal structures of the picornavirus bovine enterovirus 2 (BEV2) and the cytoplasmic polyhedrosis virus type 18 polyhedrin, with total data collection time ...[more]