Ontology highlight
ABSTRACT:
SUBMITTER: Denninghoff V
PROVIDER: S-EPMC5589730 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Denninghoff V V Olivieri E H R EHR Fresno C C Uceda A A Mota L L Suenaga A P AP Carraro D M DM Martins V R VR Avagnina A A Soares F A FA Campos A H J Fróes Marques AHJFM
Scientific reports 20170907 1
The control of pre-analytical-factors in human biospecimens collected for health research is currently required. Only two previous reports using post-mortem brain samples have tried to address the impact of cold-ischemia on tissue pH. Here we report pH variations according to time (third-order polynomial model) in mice for liver, kidney and lung samples. Tissue alkalosis in cold-ischemia time may be an underlying mechanism of gene expression changes. Therefore, tissue-pH regulation after organ r ...[more]