Ontology highlight
ABSTRACT:
SUBMITTER: Atanasov G
PROVIDER: S-EPMC5593714 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Atanasov Georgi G Dietel Corinna C Feldbrügge Linda L Benzing Christian C Krenzien Felix F Brandl Andreas A Mann Elli E Englisch Julianna Paulina JP Schierle Katrin K Robson Simon C SC Splith Katrin K Morgul Mehmet Haluk MH Reutzel-Selke Anja A Jonas Sven S Pascher Andreas A Bahra Marcus M Pratschke Johann J Schmelzle Moritz M
Oncoimmunology 20170628 8
<b>Background</b>. Tumor necrosis as well as tumor-associated macrophages (TAMs) in the tumor invasive front (TIF) have been suggested to have a prognostic value in selected solid tumors, inclusive hilar cholangiocarcinoma. However, little is known regarding their influence on tumor progression and prognosis in intrahepatic cholangiocarcinoma (iCC). <b>Methods</b>. We analyzed surgically resected tumor specimens of human iCC (n = 88) for distribution and localization of TAMs, as defined by expre ...[more]