Ontology highlight
ABSTRACT:
SUBMITTER: Rampioni G
PROVIDER: S-EPMC5596013 | biostudies-literature | 2017 Sep
REPOSITORIES: biostudies-literature
Rampioni Giordano G Pillai Cejoice Ramachandran CR Longo Francesca F Bondì Roslen R Baldelli Valerio V Messina Marco M Imperi Francesco F Visca Paolo P Leoni Livia L
Scientific reports 20170912 1
Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants. RND pumps have also been proposed to contribute to bacterial infection, implying that efflux pump inhibitors (EPIs) could also act as anti-virulence drugs. Nevertheless, EPIs are usually investigated only for their properties as antibiotic adjuvants, while their potential anti-virulence activit ...[more]