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Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom.

ABSTRACT: Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.

SUBMITTER: Durand NC

PROVIDER: S-EPMC5596920 | biostudies-literature | 2016 Jul

REPOSITORIES: biostudies-literature

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Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom.

Durand Neva C NC Robinson James T JT Shamim Muhammad S MS Machol Ido I Mesirov Jill P JP Lander Eric S ES Aiden Erez Lieberman EL

Cell systems 20160701 1

Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets. ...[more]

PMID: 27467250

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